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Autoregulated extra- and intracorporeal pump system for perfusion
1Juro Wada Commemorative Heart & Lung Institute, Yuden Clinic & Akasaka Hospital Medical Center, Tokyo, Japan.
International Surgery
|April 1, 1992
Summary
This study introduces a cybernetic approach for cardiopulmonary bypass, using sensors for feedback regulation to enhance patient safety and automate processes like weaning. The system aims to reduce serious events during perfusion by optimizing bypass flow and preventing complications.
Area of Science:
- Biomedical Engineering
- Cardiovascular Surgery
Background:
- Serious adverse events occur in 1 in every 300 cardiopulmonary bypass perfusions.
- Conventional bypass methods lack real-time feedback regulation for optimal performance.
Purpose of the Study:
- To develop a cybernetic system for real-time feedback regulation of cardiopulmonary bypass.
- To enhance patient safety by preventing complications such as overtransfusion and air embolism.
- To enable automatic weaning and facilitate partial bypass procedures.
Main Methods:
- Utilized photosensors and pressure sensors at critical circuit points for feedback.
- Implemented left atrial pressure control to prevent overtransfusion.
- Clinically tested a system to prevent air contamination in the arterial line.
Main Results:
- The cybernetic approach allows feedback regulation based on changes in venous return.
- Left atrial pressure control effectively prevents overtransfusion and enables automatic weaning.
- The test system successfully prevented gross air contamination of the arterial line.
Conclusions:
- A cybernetic system offers improved safety and automation for cardiopulmonary bypass.
- Future development includes a compact, implantable pump oxygenator for enhanced cardiac support.
- This technology promises to improve physiological perfusion management during extracorporeal circulation.