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[Aseptic meningitis during Sweet syndrome]
1Service de Dermatologie, Centre Hospitalier Saint-Philibert, Université Catholique de Lille.
Annales De Dermatologie Et De Venereologie
|February 1, 2006
Summary
Sweet syndrome, a neutrophilic skin disease, can manifest with aseptic meningitis. Early diagnosis and corticosteroid treatment are crucial for managing this rare extracutaneous complication.
Area of Science:
- Dermatology
- Neurology
- Hepatology
Background:
- Sweet syndrome is a neutrophilic dermatosis with potential systemic involvement.
- Extracutaneous manifestations, though rare, can include neurological complications.
- Aseptic meningitis is an uncommon but recognized sequela of Sweet syndrome.
Observation:
- A 42-year-old male presented with characteristic skin lesions and myalgia, diagnosed as Sweet syndrome.
- Histopathology confirmed acute neutrophilic dermatosis with inflammation and cholestasis.
- The patient developed severe headaches and meningeal irritation during corticosteroid dose reduction.
Findings:
- The patient was diagnosed with Sweet syndrome complicated by aseptic meningitis and hepatic involvement.
- Investigations for underlying digestive or hematologic diseases were negative.
- Treatment with higher-dose systemic corticosteroids led to a favorable outcome.
Implications:
- Aseptic meningitis represents a significant extracutaneous manifestation of Sweet syndrome.
- Prompt diagnosis and exclusion of infection are vital for initiating appropriate corticosteroid therapy.
- A multidisciplinary approach is essential for managing complex Sweet syndrome cases.