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[Pseudotumoral presentation of American pulmonary histioplasmosis]

J Margery1, A Bonnichon, D Jeanbourquin

  • 1Service des Maladies Respiratoires, Hôpital d'Instruction des Armées Percy, 101, avenue Henri-Barbusse, BP 406, 92140 Clamart. j.margery@wanadoo.fr

Revue De Pneumologie Clinique
|February 2, 2006
PubMed

Insights

American pulmonary histoplasmosis, a deep fungal infection, can mimic tuberculosis or cancer. This report details two immunocompetent individuals with a multinodular lung presentation of this imported mycosis.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Mycology

Background:

  • American pulmonary histoplasmosis is an imported deep mycosis caused by Histoplasma capsulatum inhalation.
  • It presents with diverse clinical and radiological features that can simulate other lung conditions.

Observation:

  • Two immunocompetent individuals working in Venezuela presented with American histoplasmosis.
  • Their cases exhibited a pseudo-tumoral form with a multinodular pulmonary presentation.

Findings:

  • Histoplasma capsulatum infection can manifest as a pseudo-tumoral form.
  • Multinodular presentation is a key radiological feature in these cases.

Implications:

  • Highlights the importance of considering imported mycoses in differential diagnoses.
  • Emphasizes the need for awareness of Histoplasma capsulatum in endemic and non-endemic settings.
  • Suggests further investigation into the pseudo-tumoral presentation of pulmonary histoplasmosis.

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