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Acute retinal necrosis syndrome.

D S Gartry1, D J Spalton, A Tilzey

  • 1St Thomas's Hospital, Department of Ophthalmology, London.

The British Journal of Ophthalmology
|May 1, 1991
PubMed
Summary

Acute retinal necrosis (ARN) is a rare viral eye condition. Varicella zoster virus (VZV) and herpes simplex virus (HSV) are the primary causes, often leading to vision loss and retinal detachment.

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Area of Science:

  • Ophthalmology
  • Virology
  • Medical Science

Background:

  • Acute retinal necrosis (ARN) is a rare but severe ocular inflammatory condition.
  • It can lead to significant and potentially permanent vision impairment.

Observation:

  • This study reviewed six cases (nine eyes) of ARN over six years.
  • Clinical features, etiology, and management strategies were analyzed.

Findings:

  • Findings support that ARN is primarily caused by varicella zoster virus (VZV) or herpes simplex virus (HSV).
  • Characteristic confluent peripheral retinal necrosis was observed in all cases, with retinal detachment occurring in three eyes.
  • Retinal arteritis was a notable diagnostic feature in one case.

Implications:

  • The study reinforces the viral etiology of ARN, emphasizing the roles of VZV and HSV.
  • Early diagnosis and management are crucial to mitigate vision loss and complications like retinal detachment.
  • ARN is predominantly a unilateral condition, affecting approximately 65% of cases.

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