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Published on: December 4, 2020
Risk factors for cervicitis among women with bacterial vaginosis
Jeanne M Marrazzo1, Harold C Wiesenfeld, Pamela J Murray
1Department of Medicine, University of Washington, Seattle 98104, and Department of Pediatrics, Children's Hospital of Pittsburgh, PA, USA. jmm2@u.washington.edu
Background:
Cervicitis commonly occurs in women with bacterial vaginosis (BV), often without concomitant chlamydial or gonococcal infection. The risk factors for cervicitis have not been described.
Methods:
We characterized the risk factors for cervicitis, which is defined as endocervical mucopurulent discharge or easily induced bleeding, among women with BV who were 14-45 years of age. Associations between cervicitis and the characteristics of the subjects, including the presence of specific vaginal bacteria and chlamydial or gonococcal infection detected by strand displacement assay, were analyzed.
Results:
Of 424 women with BV, 63 (15%) had cervicitis. Of these 63 women, only 8 (13%) had chlamydia or gonorrhea. The risk factors for cervicitis, adjusted for variables, included older age (P<.001, for trend),
Conclusions:
Cervicitis is common among women with BV and is associated with some risk factors that are distinct from those associated with endocervical infection with Neisseria gonorrhoeae or Chlamydia trachomatis. Absence of H2O2-producing lactobacilli may contribute to the development of cervicitis.
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