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Published on: February 23, 2018
Measurement of diffusion through calcium alginate gel matrices
O Holte1, H H Tønnesen, J Karlsen
1School of Pharmacy, University of Oslo, Norway.
Abstract:
The diffusion of high molecular weight dextran samples and low molecular weight quinine sulphate in homogenous calcium alginate gel matrices was studied. An experimental design suitable for studying the diffusion of substances from or through a gel sample was established. The experimental results indicate that the different types of molecules diffuse in the gel by different mechanisms. The diffusion rate of the molecules in the gel is dependent on gel composition.

