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Epithelial lacrimal gland tumors: a clinicopathological study of 18 cases
Danyel E C Perez1, Fábio R Pires, Oslei P Almeida
1Department of Oral Pathology, School of Dentistry of Piracicaba/UNICAMP, Piracicaba, São Paulo, Brazil. perezdec2003@yahoo.com.br
Objective:
The aim of this study was to report the clinicopathological features of 18 epithelial tumors of the lacrimal gland treated in a single institution.
Study Design And Setting:
Clinical data and treatment were recorded and histological features reviewed.
Results:
Twelve tumors (66.7%) were adenoid cystic carcinoma (ACC), 5 (27.8%) pleomorphic adenoma (PA), and 1 (5.5%) carcinoma ex pleomorphic adenoma. All patients with ACC presented with advanced clinical stage, and most were treated by wide surgical resection followed by adjuvant radiotherapy. No recurrence was observed in 4 cases of ACC; however, 7 patients died from persistence of disease or by local and/or distant recurrence. All PA patients were successfully treated by surgical resection.
Conclusions:
Epithelial lacrimal gland tumors are mainly PA and ACC, and malignancies are more common than benign tumors. Although ACC presented typically with advanced clinical stage, 33% of the patients survived without tumor recurrence or metastasis.
