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Serum leptin levels in patients with allergic rhinitis
Murat Unal1, Gülçin Eskandari, Necati Muşlu
1Department of Biochemistry, Mersin University, School of Medicine, Mersin, Turkey. munal@mersin.edu.tr
Objective:
To investigate the serum leptin levels in patients with allergic rhinitis during the symptomatic period.
Study Design And Setting:
A randomized, prospective study was performed on 26 adult patients with allergic rhinitis and 20 control subjects with similar age, sex and body mass index in a tertiary otolaryngology center.
Results:
Leptin levels were 28.8 +/- 14.1 ng/mL in the patients with allergic rhinitis, and 20.8 +/- 13.5 ng/mL in the control group respectively. The difference between the groups was statistically significant (p = 0.04).
Conclusion:
Serum leptin levels were found to be significantly higher in patients with allergic rhinitis in symptomatic period.
Significance:
Apart from its primary role in the regulation of body weight and energy expenditure, leptin may have a role in the inflammatory process of the allergic rhinitis.
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