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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Dual-acquisition phase-sensitive fat-water separation using balanced steady-state free precession
Brian A Hargreaves1, Neal K Bangerter, Ann Shimakawa
1Department of Radiology, Stanford University, Stanford, CA 94305-5488, USA.
Magnetic Resonance Imaging
|February 4, 2006
Summary
A new dual-acquisition phase-sensitive SSFP method separates fat and water signals and reduces image artifacts. This advance improves magnetic resonance imaging feasibility, especially at high magnetic field strengths.
Area of Science:
- Medical Imaging
- Magnetic Resonance Imaging Physics
Background:
- Balanced steady-state free precession (SSFP) sequences offer high signal and contrast in short scan times.
- Clinical use of balanced SSFP is limited by bright fat signals and signal voids from off-resonance effects.
Purpose of the Study:
- To introduce a novel dual-acquisition phase-sensitive SSFP method.
- To address limitations of standard balanced SSFP, specifically fat signal and off-resonance artifacts.
Main Methods:
- Combines two standard balanced SSFP acquisitions.
- Acquisitions are added in quadrature and phase corrected.
- Fat and water separation achieved by signal sign analysis.
Main Results:
- Successfully separates fat and water signals.
- Simultaneously reduces signal voids caused by off-resonance effects.
- Method is particularly effective at high magnetic field strengths.
Conclusions:
- Dual-acquisition phase-sensitive SSFP enhances clinical feasibility of balanced SSFP.
- The technique can be combined with other preparation schemes for tailored contrast.
- Offers improved fat-water separation and artifact reduction in MRI.
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