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Published on: September 9, 2020
[The effect of limb salvage on treating osteosarcoma with pathological fracture in two cases]
Dingfeng Li1, Qiu Cui, Lei Wang
1Department of Orthopaedics, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100039, P R China. 307yygk@sina.com
Objective:
To investigate the effect of limb salvage on treating osteosarcoma with pathological fracture.
Methods:
From October 2002 to January 2003, 2 cases of osteosarcoma with pathological fracture were treated by limb salvage. Intra-arterial chemotherapy was given by subcutaneous implantable delivery system with caffeine. Replacement with prosthesis was performed after 5 times of chemotherapy.
Results:
Two patients were followed up for twenty-four months and 21 months respectively. No infection, aseptic loosening, local recurrence or metastasis occurred, and function recovery of joints was satisfactory.
Conclusion:
Limb salvage can be considered in condition that primary osteosarcoma with pathological fracture can be treated by effective and comprehensive chemotherapy.
