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Published on: September 22, 2020
Neuropsychological morbidity linked to childhood sleep-disordered breathing
Ann C Halbower1, E Mark Mahone
1Eudowood Division of Respiratory Science, Johns Hopkins University School of Medicine, Baltimore, MA 21287, USA. ahalbowe@jhmi.edu
Insights
Mild sleep apnea in children can cause neuropsychological deficits, but some cognitive issues may improve with treatment. Further research is needed to understand long-term effects on the developing brain.
Area of Science:
- Pediatric Neurology
- Developmental Psychology
- Sleep Medicine
Background:
- Sleep disorders in children present unique challenges due to rapid cognitive and neurobehavioral development.
- Mild sleep apnea and snoring are increasingly linked to neuropsychological deficits in pediatric populations.
- The long-term impact of these deficits on a child's development requires thorough investigation.
Purpose of the Study:
- To investigate the long-term neuropsychological consequences of sleep disorders in children.
- To explore the potential reversibility of cognitive deficits following treatment for mild sleep apnea.
- To identify factors influencing the long-term outcomes of treated sleep-disordered breathing in children.
Main Methods:
- Review of recent studies linking sleep apnea and snoring to neuropsychological deficits.
- Analysis of preliminary data on cognitive function changes after treatment for mild sleep apnea.
- Exploration of critical periods of brain plasticity and their interaction with sleep-disordered breathing.
Main Results:
- Mild sleep apnea and snoring are associated with neuropsychological function deficits in children.
- Preliminary findings suggest some cognitive deficits may be reversible after treatment.
- Factors like age at treatment and duration of sleep-disordered breathing may impact long-term outcomes.
Conclusions:
- Sleep-disordered breathing in children can lead to significant neuropsychological consequences.
- Treatment may offer partial reversal of cognitive deficits, but long-term outcomes vary.
- Further research is crucial to understand the impact on brain plasticity and potential permanent effects.
Abstract:
Understanding the long-term neuropsychological consequences of sleep disorders in children poses a significant challenge to researchers. Since children are in a state of rapidly changing cognition and neurobehavioral function, impacts on development may have profound consequences. Recent studies now demonstrate that mild sleep apnea and snoring, once considered within the spectrum of normal sleep patterns, are associated with deficits of neuropsychological function. Preliminary data suggest that some of these cognitive deficits may be reversible following treatment of mild sleep apnea in children; however, factors such as age at treatment, duration of sleep disordered breathing, pre-morbid intellectual level, socioeconomic status, or the effectiveness of treatment may adversely affect long-term outcome. Furthermore, it is imperative that researchers determine whether the developing brain exhibits critical periods of plasticity during which episodes of sleep-disordered breathing might cause long-term or permanent neuropsychological effects.
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