Related Experiment Video

Updated: Aug 11, 2026

Amikacin Protection Assay for Quantification and Visualization of Escherichia coli Cell Invasion
09:22

Amikacin Protection Assay for Quantification and Visualization of Escherichia coli Cell Invasion

Published on: July 3, 2026

[Meningitis caused by Enterococcus faecalis during disseminated anguilluliasis]

Jean-Ralph Zahar1, Jacques Tankovic, Emilie Catherinot

  • 1Service de réanimation polyvalente, Institut Gustave Roussy, Villejuif. jean-ralph.zahar@nck.ap-hop-paris.fr

Presse Medicale (Paris, France : 1983)
|February 8, 2006
PubMed
Abstract

Insights

Disseminated anguilluliasis can cause serious complications like meningitis, often from Gram-negative bacteria. Early ivermectin treatment is recommended for immunocompromised individuals with potential exposure, even without definitive diagnosis.

Area of Science:

  • Infectious Diseases
  • Tropical Medicine
  • Neurology

Background:

  • Disseminated anguilluliasis is a severe helminthic infection.
  • Bacterial meningitis is a known complication, typically involving Gram-negative bacteria.
  • Immunosuppression increases the risk of severe Strongyloides stercoralis infection.

Observation:

  • A case of meningitis in an immunocompromised patient previously treated for T-lymphoma.
  • Cerebrospinal fluid and bronchoalveolar lavage cultures identified Enterococcus faecalis.
  • Strongyloides stercoralis was detected in stool and bronchoalveolar lavage samples.

Findings:

  • Enterococcus faecalis, a Gram-positive bacterium, was identified as the causative agent of meningitis.
  • Co-infection with Strongyloides stercoralis was confirmed.
  • The patient showed a favorable outcome with appropriate treatment.

Implications:

  • Highlights the importance of considering Strongyloides stercoralis in immunocompromised patients, even with atypical bacterial pathogens.
  • Suggests presumptive ivermectin treatment for at-risk individuals with potential exposure, regardless of parasitological confirmation.
  • Emphasizes the need for early diagnosis and management of disseminated anguilluliasis to prevent severe complications.

More Related Videos

Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment09:25

Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment

Published on: February 22, 2017

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...