Related Experiment Video
Updated: Aug 11, 2026

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials
Published on: April 19, 2024
[Non-randomized evaluation studies (TREND)]
Carles Vallvé1, Maite Artés, Erik Cobo
1Farmacólogo clínico, Cardedeu, Barcelona, España. vallve@telefonica.net
Abstract:
Nonrandomized intervention trials are needed when randomized clinical trials cannot be performed. To report the results from nonrandomized intervention studies transparently, the TREND (Transparent Reporting of Evaluations with Nonrandomized Designs) checklist should be used. This implies that nonrandomized studies should follow the remaining methodological tools usually employed in randomized trials and that the uncertainty introduced by the allocation mechanism should be explicitly reported and, if possible, quantified.
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