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Intensive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trial
Jens Søndergaard1, Annette Foged, Jakob Kragstrup
1Research Unit for General Practice, University of Aarhus, Aarhus, Denmark. js@alm.au.dk
Objective:
To evaluate the impact of an intensive pharmaceutical care campaign targeting inappropriate use of triptans.
Design:
Randomized controlled trial.
Setting:
22 community pharmacies in the County of Funen, Denmark.
Subjects:
A total of 1123 triptan users at intervention pharmacies and 1340 at control pharmacies.
Intervention:
Intervention pharmacy staff received information on migraine and other types of headache, detection of inappropriate triptan use and other drug-related problems, and techniques for establishing a dialogue with patients. Intervention consisted of a folder and a structured dialogue with the pharmacy staff. The folder included questions aimed at detecting overuse and inappropriate triptan use.
Main Outcome Measures:
Change in average triptan consumption in doses per month measured by means of a prescription database with information on all purchases of reimbursed drugs at the level of the individual patient.
Results:
Overall, intervention had no statistically significant short-term impact on patients' consumption of triptans either among incident users (intervention/control ratio 1.02; 95% confidence interval 0.95 to 1.12), or among prevalent users (1.02; 0.97 to 1.08). No effects were observed after 6 and 9 months, apart from a possible borderline effect after 9 months among prevalent users with intermediate triptan consumption (0.93; 0.87 to 1.00).
Conclusion:
The pharmaceutical care campaign did not reduce the use of triptans.
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