[Pre-clinical and clinical studies on bone morphogenetic proteins for regenerative therapies in dentistry field]

Many researches were done on the application of bone morphogenetic proteins (BMPs) for periodontal regeneration, and bone regeneration followed by the insertion of dental implants. There are many reports which suggested that BMPs enhanced alveolar bone and cementum formations in the pre-clinical studies on periodontal regeneration. However, it is suggested that ankylosis might disturb the ideal periodontal regeneration. There are also many reports which suggested that BMPs were effective for alveolar ridge augmentation for the insertion of dental implant in pre-clinical and clinical studies. There are great hopes that the application of BMPs for the regenerative therapies on diseases involving bone loss.