Related Experiment Video
Updated: Aug 11, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Published on: April 6, 2017
[How should inhaled corticosteroids be prescribed in asthma?]
A new approach for persistent asthma uses budesonide/formoterol as both maintenance and reliever medication, allowing patients to self-adjust doses based on symptoms. This review discusses the benefits and potential drawbacks of this innovative asthma management strategy.
Area of Science:
- Respiratory Medicine
- Pharmacology
Context:
- Current persistent asthma treatment relies on separate maintenance and reliever therapies.
- Inhaled corticosteroids and long-acting beta-2-agonists are standard maintenance treatments.
- Short-acting beta-2-agonists are typically used for quick symptom relief.
Purpose:
- To review the novel approach of using budesonide/formoterol as a single inhaler for both maintenance and reliever therapy in persistent asthma.
- To discuss the potential advantages and disadvantages of patient-led, symptom-based adjustment of asthma medication.
Summary:
- A budesonide/formoterol combination inhaler is proposed for both daily maintenance and on-demand symptom relief in persistent asthma.
- This strategy empowers patients to self-manage their asthma by adjusting medication frequency based on symptom severity.
- The review will explore the efficacy, safety, and practical implications of this integrated treatment model.
Impact:
- This approach could simplify asthma management and improve patient adherence.
- It may offer a more personalized and responsive treatment option for individuals with persistent asthma.
- Understanding the benefits and risks is crucial for clinical adoption and patient outcomes.
Related Concept Videos
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Inhaled Medications
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
COPD: Management Using Bronchodilators and Corticosteroids
Antiasthma Drugs: β2-Adrenoceptor Agonists
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
