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Updated: Jul 3, 2026

Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System
Published on: May 12, 2023
[Cardiogenetics in clinical practice : challenges, indications, and perspectives]
Henri Margot1,2, Michel Guipponi1,2, Thomas Rio Frio1,2
1Service de médecine génétique, Département diagnostique, Hôpitaux universitaires de Genève, 1211 Genève 14.
Insights
Cardiogenetics is crucial for managing heart diseases by using genetic data for diagnosis, treatment, and prevention. Integrating genetic analysis with clinical information optimizes patient care and enables family screening for personalized cardiology.
Area of Science:
- Cardiology
- Genetics
- Precision Medicine
Abstract:
Cardiogenetics plays an increasingly important role in managing cardiovascular diseases, owing to the major impact of genetic data on diagnosis, risk stratification, therapeutic decision-making, and family-based prevention. Many cardiomyopathies, channelopathies, and other entities have a genetic basis, which is often monogenic, with incomplete penetrance and variable expressivity. Genetic analyses, now integrated into international guidelines, must be interpreted in the context of the clinical phenotype and family history, complemented by cardiological screening. Their rational use helps optimize patient management, enables cascade screening of relatives, and paves the way for more personalized and preventive cardiology.
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