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Epiglottic and base-of-tongue prolapse in children: grading and management
1Airway and Voice Center, the Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, and the Department of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. yellra@chp.edu
Insights
Epiglottic and base-of-tongue (EBT) prolapse causes pediatric airway obstruction. A new grading system successfully classified EBT prolapse severity, revealing high rates of swallowing dysfunction and reflux.
Area of Science:
- Pediatric Otolaryngology
- Pediatric Pulmonology
- Pediatric Gastroenterology
Background:
- Airway obstruction in children can arise from various causes, including anatomical abnormalities.
- Epiglottic and base-of-tongue (EBT) prolapse is a recognized, though less common, cause of upper airway obstruction in pediatric patients.
- Understanding the spectrum and associated comorbidities of EBT prolapse is crucial for effective management.
Purpose of the Study:
- To define epiglottic and base-of-tongue (EBT) prolapse as a distinct entity causing airway obstruction in children.
- To describe laryngopharyngeal findings, swallowing dysfunction, and gastroesophageal reflux disease (GERD) in children with EBT prolapse.
- To introduce and evaluate a novel grading system for EBT prolapse severity.
Main Methods:
- A prospective study involving 14 pediatric patients diagnosed with EBT prolapse.
- Flexible fiberoptic nasopharyngolaryngoscopy was utilized for detailed airway assessment.
- A new grading system (Grade 0-3) was developed to categorize the severity of EBT prolapse based on anatomical obstruction.
Main Results:
- The study successfully applied the new grading system to 14 children, classifying their EBT prolapse severity.
- Grade 1 EBT prolapse was observed in 50% of patients, Grade 2 in 29%, and Grade 3 in 21%.
- High prevalence of associated conditions was noted: swallowing dysfunction in 38% and gastroesophageal reflux disease in 93% of cases.
Conclusions:
- The developed grading system effectively quantifies the severity and location of airway obstruction in pediatric EBT prolapse.
- Swallowing dysfunction and GERD are common comorbidities in children with EBT prolapse.
- While surgical options exist, continuous positive airway pressure (CPAP) or tracheotomy may represent safer management strategies due to inconsistent surgical success and aspiration risks.
Objectives:
A distinct entity of airway obstruction from epiglottic and base-of-tongue (EBT) prolapse in the pediatric population is defined. Laryngopharyngeal findings, swallowing dysfunction, and gastroesophageal reflux disease are described in a group of children with EBT prolapse. A new grading system is also presented.
Study Design:
A prospective study was conducted of laryngopharyngeal findings in children with EBT prolapse, a description of a new grading system, and review of the pediatric literature.
Methods:
Fourteen children with EBT prolapse were prospectively studied with flexible fiberoptic nasopharyngolaryngoscopy. A new grading system for EBT prolapse was developed. Grade 0 is a normal airway. Grade 1 is prolapse of the epiglottis against the posterior pharyngeal wall but with normal position of the tongue. Grade 2 is prolapse of the epiglottis and base of tongue with only the epiglottic tip visible. Grade 3 is glossoptosis with no portion of the epiglottis visible. The diagnostic modalities and treatments for EBT prolapse are reviewed.
Results:
Of the 14 children studied, seven (50%) had grade 1, four (29%) had grade 2, and three (21%) had grade 3 EBT prolapse. Swallowing dysfunction (five of 14, 38%) and gastroesophageal reflux disease (13 of 14, 93%) were also prevalent.
Conclusion:
The new grading system was applied successfully to describe the severity and sites of airway obstruction in 14 children with EBT prolapse. Swallowing dysfunction and gastroesophageal reflux disease occur in this population. Although surgical therapies are sometimes effective, lack of consistent success and the risk of aspiration with procedures other than tracheotomy may lead some to conclude that continuous positive airway pressure or tracheotomy are the safest options.
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