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Risk factor of birth weight below 2,500 grams and attention deficit hyperactivity disorder in Thai children

Chadapim Sasaluxnanon1, Titawee Kaewpornsawan

  • 1Division of Child Psychiatry, Department of Psychiatry, Faculty of Medical, Siriraj Hospital, Mahidol University, 2 Prannok Rd. Bangkoknoi, Bangkok 10700, Thailand. sornsasa@hotmail.com

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|February 14, 2006
PubMed

Insights

Low birth weight (below 2,500 grams) is a significant risk factor for Attention Deficit Hyperactivity Disorder (ADHD). Other identified risks include pregnancy complications, maternal emotional distress, and family history of ADHD.

Area of Science:

  • Pediatric Psychiatry
  • Neurodevelopmental Disorders
  • Public Health

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder impacting children.
  • Identifying risk factors for ADHD is crucial for early intervention and prevention strategies.

Purpose of the Study:

  • To investigate the association between low birth weight (below 2,500 grams) and ADHD.
  • To identify other potential risk factors contributing to ADHD development.

Main Methods:

  • A hospital-based, retrospective case-control study involving 122 ADHD cases and 119 controls.
  • Data collected via questionnaires on demographic, prenatal, and postnatal factors, including birth weight and family history.
  • Multiple logistic regression analysis was employed to assess the influence of various factors.

Main Results:

  • ADHD cases were 3.6 times more likely to have a birth weight below 2,500 grams compared to controls (p=0.03).
  • Significant risk factors identified include pregnancy complications (OR=4.17), emotional distress during pregnancy (OR=2.99), postnatal complications (OR=3.26), and a family history of ADHD (OR=3.6).

Conclusions:

  • Low birth weight, pregnancy complications, maternal emotional distress, neonatal complications, and a family history of ADHD are potential risk factors for developing ADHD.
  • These findings highlight the importance of prenatal and perinatal care in mitigating ADHD risk.
Abstract

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