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Updated: Aug 11, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

Dizinc alkoxides and amides supported by binucleating bis(amidoamine) ligands

Mark L Hlavinka1, Michael J McNevin, Richard Shoemaker

  • 1Department of Chemistry and Biochemistry, University of Colorado, Boulder, 80309-0215, USA.

Inorganic Chemistry
|February 14, 2006
PubMed

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Azide ions act as good nucleophiles and react with unhindered alkyl halides to form alkyl azides. Alkyl azides do not participate in further nucleophilic substitution reactions, thereby eliminating the chances of polyalkylated products. Alkyl azides are reduced by hydride-based reducing agents, like lithium aluminum...
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