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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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Nitro radical anion formation from nitrofuryl substituted 1,4-dihydropyridine derivatives in mixed and non-aqueous

J Argüello1, L J Núñez-Vergara, S Bollo

  • 1Bioelectrochemistry Laboratory, Chemical and Pharmaceutical Sciences Faculty, University of Chile, POB 233, Santiago 1, Chile.

Bioelectrochemistry (Amsterdam, Netherlands)
|February 14, 2006
PubMed

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Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
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