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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
[S-phase fraction of benign mastopathies and breast carcinomas]
1Institut für Pathologie, Bezirkskrankenhaus Potsdam.
Zentralblatt Fur Chirurgie
|January 1, 1991
Abstract:
The S phase fraction of breast biopsies of 110 patients determined in vitro using 3H-thymidine. In fibrocystic lesions the 3H-thymidine labeling index (3H-TMI) increases parallel to the degree of dysplasia. In our opinion proliferating mastopathies are only those with a 3H-TMI of more than 1%. Invasive ductal mammary carcinomas with the histological structure demonstrate a strong variable proliferative activity histoautoradiographically as expression of their different growth dynamics.

