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[Eccrine squamous syringometaplasia from chemotherapy extravasation].
María Teresa Bordel1, Alberto Miranda
1Servicio de Dermatología, Hospital Clínico Universitario de Valladolid, Facultad de Medicina de Valladolid, Spain. matebordel@yahoo.es
Actas Dermo-Sifiliograficas
|February 16, 2006
Summary
Eccrine squamous syringometaplasia is a rare skin reaction seen after chemotherapy. This case highlights its occurrence following lung cancer treatment and accidental drug extravasation.
Area of Science:
- Dermatology
- Oncology
Background:
- Eccrine squamous syringometaplasia is a rare condition.
- It is associated with chemotherapy, chronic ulcers, skin tumors, drug ingestion, toxic agents, and inflammatory processes.
Observation:
- A 47-year-old male with microcytic lung carcinoma and superior vena cava syndrome developed an erythematous plaque after chemotherapy.
- The patient experienced accidental extravasation of chemotherapy drugs.
Findings:
- Histopathological examination revealed eccrine squamous syringometaplasia.
- Interphase dermatitis and epidermal changes potentially causing epidermal necrosis were also observed.
Implications:
- This case expands the understanding of triggers for eccrine squamous syringometaplasia.
- It underscores the importance of recognizing this rare dermatologic reaction in patients undergoing chemotherapy, especially after extravasation events.