[Granuloma from liquid silicone]

Area of Science:

• Dermatology
• Pathology
• Plastic Surgery

Background:

• Increased demand for cosmetic soft tissue augmentation using injectable substances.
• Apparent safety of these cosmetic procedures often overshadows potential adverse reactions.
• Foreign body granulomas are a known complication associated with various injectable materials.

Observation:

• A female patient presented with inflammatory facial lesions.
• The lesions were diagnosed via histopathological examination.
• Histopathology revealed a foreign body granuloma.

Findings:

• The granuloma was definitively linked to the use of liquid silicone.
• Liquid silicone injections, despite perceived safety, can trigger inflammatory responses.
• Histopathological analysis is crucial for diagnosing such complications.

Implications:

• Highlights the risk of granuloma formation from liquid silicone fillers.
• Underscores the importance of thorough patient history and histopathological diagnosis in cosmetic complications.
• Suggests a need for re-evaluation of the long-term safety profile of injectable cosmetic materials.