Related Experiment Video
Updated: Aug 11, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Focal epithelial hyperplasia]
Yolanda Delgado1, Antonio Torrelo, Isabel Colmenero
1Servicio de Dermatología, Hospital Niño Jesús, Madrid, Spain.
Abstract:
Focal epithelial hyperplasia (FEH) is a benign proliferation of the oral mucosa with well defined clinical and histological characteristics. It has been associated with infection of the oral mucosa by types 13 and 32 of the human papillomavirus (HPV), and to a lesser extent, with other types. Its clinical course is variable, although it usually persists for months or years; cases with spontaneous resolution have been described, as have others with prolonged persistence. We present the case of an Ecuadorian boy whose visit was motivated by lesions in the oral mucosa consistent with a diagnosis of FEH, which were confirmed in the histological study, and in which HPV type 13 DNA was identified.
Insights
Focal epithelial hyperplasia (FEH), a benign oral condition, is linked to human papillomavirus (HPV). This case study confirms HPV type 13 in an Ecuadorian boy with FEH, highlighting the virus
Area of Science:
- Oral pathology and viral infections.
Background:
- Focal epithelial hyperplasia (FEH) is a benign oral mucosa proliferation.
- FEH is primarily associated with human papillomavirus (HPV) types 13 and 32.
Observation:
- A case report of an Ecuadorian boy presenting with oral mucosal lesions.
Findings:
- Clinical and histological examination confirmed Focal epithelial hyperplasia.
- Human papillomavirus (HPV) type 13 DNA was identified in the lesions.
Implications:
- This case reinforces the association between HPV type 13 and FEH.
- Understanding the viral etiology aids in managing this benign oral condition.
Related Concept Videos
Cellular Adaptation III: Hyperplasia
Cellular Adaptation IV: Dysplasia and Metaplasia
Classification of Epithelial Tissues: Glandular Epithelium
Multicellular glands are formed during early development when epithelial budding...
Abnormal Proliferation
Abnormal Proliferation
Classification of Epithelial Tissues: Stratified Epithelium
