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Advancing glycomics: implementation strategies at the consortium for functional glycomics
Rahul Raman1, Maha Venkataraman, Subu Ramakrishnan
1Center for Biomedical Engineering, Massachusetts Institute of Technology; Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Glycomics, the study of complex carbohydrates, requires bioinformatics platforms. The Consortium for Functional Glycomics (CFG) developed databases and tools to manage and share glycomics data for advancing research.
Area of Science:
- Biochemistry
- Bioinformatics
- Genomics
Background:
- Glycomics, the study of glycans, is crucial in the post-genomics era.
- Large-scale initiatives are generating vast amounts of glycomics data.
- Developing bioinformatics platforms is essential for managing this data.
Purpose of the Study:
- To review the databases and bioinformatics platform developed by the Consortium for Functional Glycomics (CFG).
- To illustrate how these resources advance the field of glycomics.
Main Methods:
- The review focuses on the bioinformatics platform and databases of the CFG.
- It analyzes the strategies for data acquisition, integration, and dissemination.
Main Results:
- The CFG has established a comprehensive bioinformatics platform.
- This platform effectively manages and disseminates diverse glycomics datasets.
- The developed resources support structure-function relationship studies.
Conclusions:
- Bioinformatics platforms are vital for the advancement of glycomics.
- The CFG model demonstrates a successful approach to data management in glycomics.
- Integrated data resources accelerate discoveries in glycan research.
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