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Systemic assessments utilizing saliva: part 1 general considerations and current assessments
Michael D Forde1, Sreenivas Koka, Steven E Eckert
1Division of Prosthodontics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
The International Journal of Prosthodontics
|February 17, 2006
Summary
Saliva is a useful diagnostic fluid for measuring systemic conditions. Part 2 of this review focuses on using saliva to assess bone turnover, particularly for osteoporosis diagnosis.
Area of Science:
- Biochemistry
- Clinical Diagnostics
- Biomarker Discovery
Background:
- Saliva is a readily accessible biofluid with potential for non-invasive diagnostics.
- Current research explores saliva's utility beyond oral health, extending to systemic disease monitoring.
- Understanding systemic conditions through salivary analysis is an evolving field.
Purpose of the Study:
- To review the established applications of saliva in diagnosing systemic conditions.
- To specifically examine the role of salivary biomarkers in assessing bone turnover.
- To highlight the diagnostic potential of saliva for osteoporosis.
Main Methods:
- Systematic literature review of diagnostic studies utilizing salivary biomarkers.
- Analysis of existing research on saliva composition and its correlation with systemic health.
- Focus on studies investigating bone turnover markers in saliva.
Main Results:
- Saliva analysis currently supports the diagnosis of various systemic conditions.
- Emerging evidence indicates salivary markers can reflect bone metabolic activity.
- Specific salivary components show promise for non-invasive osteoporosis assessment.
Conclusions:
- Saliva serves as a valuable diagnostic fluid for systemic health monitoring.
- Further research into salivary bone turnover markers can enhance osteoporosis detection.
- Salivary diagnostics offer a promising, minimally invasive approach to healthcare.