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Updated: Aug 11, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
Published on: November 10, 2023
Subacute airway obstruction from a tracheal mucosal flap
1Anaesthetic Registrar, Department of Paediatric Anaesthesia, Women's and Children's Hospital, 72 King William Road, North Adelaide, South Australia, 5006.
A rare tracheal mucosal flap caused a life-threatening airway obstruction in a teenager after intubation. Prompt bronchoscopy and tube placement successfully resolved the obstruction, leading to full recovery.
Area of Science:
- Medicine
- Pulmonology
- Critical Care Medicine
Background:
- Tracheal intubation, while essential, carries risks including post-extubation airway complications.
- Obstructive tracheal lesions can present as stridor and respiratory distress, mimicking other conditions.
Observation:
- A 15-year-old female developed acute respiratory distress and stridor 29 hours after 35 hours of intensive care unit intubation.
- Initial management, including re-intubation, failed to secure a patent airway.
Findings:
- Urgent bronchoscopy revealed an 80% obstructive tracheal mucosal flap in the subglottic region.
- Successful management involved precise fiberoptic bronchoscope-guided placement of an endotracheal tube distal to the flap.
Implications:
- This case highlights a rare but critical cause of post-extubation stridor, emphasizing diagnostic challenges.
- Early recognition and specialized airway management are crucial for favorable outcomes in such life-threatening tracheal lesions.
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