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Intracranial xanthoma: long-term follow-up MR findings
1Department of Diagnostic Radiology, College of Medicine, Inje University, Ilsan Paik Hospital, Jyonggi-do, Koyangsi, South Korea.
Summary:
We report the serial MR findings and histologic features of intracerebral xanthoma in a patient with hyperlipidemia. MR imaging revealed nodule formations with variable degrees of edema and enhancement in the perivascular spaces. In some lesions, high-signal-intensity foci were observed on unenhanced T1-weighted images, which suggest lipid contents of the lesion.
Insights
Intracerebral xanthoma, a rare condition linked to hyperlipidemia, presents unique findings on magnetic resonance imaging (MRI). These include nodular lesions with edema and enhancement, and T1-weighted signals suggesting lipid content.
Area of Science:
- Neurology
- Radiology
- Pathology
Background:
- Intracerebral xanthoma is a rare condition.
- Hyperlipidemia is a known risk factor.
Observation:
- Serial MRI was performed.
- Histologic features were analyzed.
Findings:
- MRI revealed nodule formations in perivascular spaces.
- Lesions showed variable edema and enhancement.
- High-signal-intensity foci on T1-weighted images suggested lipid content.
Implications:
- MRI findings can aid in diagnosing intracerebral xanthoma.
- Understanding these features is crucial for patient management.