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Related Experiment Videos

Panic and fear induced by deep brain stimulation.

N A Shapira1, M S Okun, D Wint

  • 1Department of Psychiatry, University of Florida, Gainesville, FL, USA.

Journal of Neurology, Neurosurgery, and Psychiatry
|February 18, 2006
PubMed
Summary
This summary is machine-generated.

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Deep brain stimulation (DBS) in the anterior limb of the internal capsule and nucleus accumbens region can cause panic attacks. This response may involve limbic and autonomic network activation.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Neurosurgery

Background:

  • Deep brain stimulation (DBS) is used for various neurological conditions.
  • Mood, cognitive, and behavioral changes are known side effects of DBS in specific brain regions.

Observation:

  • This study investigated panic and fear as potential side effects of DBS.
  • A patient with obsessive-compulsive disorder (OCD) underwent intraoperative DBS in the anterior limb of the internal capsule and nucleus accumbens region.

Findings:

  • DBS at a specific contact in this region triggered a severe panic attack in the patient.
  • Symptoms included fear, feeling hot, and a significant heart rate increase, which ceased upon device deactivation.

Implications:

Related Experiment Videos

  • DBS in the anterior limb of the internal capsule and nucleus accumbens region can induce panic.
  • This effect likely results from the activation of limbic and autonomic neural networks.