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Nonpalpable breast lesions: stereotactic automated large-core biopsies
S H Parker1, J D Lovin, W E Jobe
1Radiology Imaging Associates, Englewood, CO 80111.
Radiology
|August 1, 1991
Summary
Stereotactic breast biopsy using a 14-gauge needle showed high agreement with surgical biopsy results for suspicious lesions. This automated gun biopsy can be a reliable alternative to surgical biopsy for diagnosing breast abnormalities.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Mammographically detected suspicious breast lesions often require biopsy for diagnosis.
- Surgical biopsy has been the traditional method, but minimally invasive techniques are increasingly explored.
Purpose of the Study:
- To evaluate the diagnostic accuracy and agreement between automated 14-gauge gun biopsy and subsequent surgical biopsy for nonpalpable breast lesions.
- To determine if stereotactic gun biopsy is a viable alternative to surgical excision.
Main Methods:
- One hundred two patients with suspicious, nonpalpable lesions underwent stereotactic biopsy with a 14-gauge automated cutting needle.
- A localization wire was placed post-biopsy, followed by surgical biopsy.
- Histologic results from both biopsy methods were compared.
Main Results:
- Histologic agreement between gun biopsy and surgical biopsy was 96% (98/102 cases).
- Agreement for carcinomas was 96% (22/23 cases), with a kappa of 0.936.
- The gun biopsy correctly diagnosed two lesions missed by surgery; two lesions were missed by gun biopsy but found at surgery.
Conclusions:
- Automated 14-gauge needle biopsy demonstrates high concordance with surgical biopsy for suspicious breast lesions.
- Stereotactic biopsy with an automated needle and gun is a potentially acceptable alternative to surgical biopsy, improving diagnostic agreement.