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Updated: Aug 11, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
Hydrogen sulphide--a novel mediator of inflammation?
Ling Li1, Madhav Bhatia, Philip K Moore
1Cardiovascular Biology Research Group, Department of Pharmacology, Yong Loo Lin School of Medicine, Block MD2, 18 Medical Drive, National University of Singapore, Singapore 117597.
Abstract:
Hydrogen sulphide (H2S) is a naturally occurring gas synthesized from cysteine. It exhibits vasodilator activity (most probably by opening vascular smooth muscle K(ATP) channels), influences leucocyte chemotaxis and promotes vascular smooth muscle cell apoptosis. Increased biosynthesis of H2S has been demonstrated in animal models of septic/endotoxic and haemorrhagic shock, pancreatitis and carrageenan-evoked hindpaw oedema in the rat. In each case, pharmacological inhibition of H2S biosynthesis is anti-inflammatory.
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