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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
[Anterior ischemic optic neuropathy and polyarteritis nodosa: case report]
Christie Michelle Graf1, Thelma Larocca Skare, Carlos Augusto Moreira
1Serviço de Oftalmologia, Hospital Universitário Evangélico de Curitiba, Curitiba, PR, Brazil. chrili@terra.com.br
Arquivos Brasileiros De Oftalmologia
|February 24, 2006
Summary
Polyarteritis nodosa, a rare condition, can cause anterior ischemic optic neuropathy. This case highlights a rare manifestation in a patient treated with cytostatics and corticosteroids.
Area of Science:
- Rheumatology
- Ophthalmology
- Neurology
Background:
- Polyarteritis nodosa (PAN) is a systemic vasculitis affecting medium-sized arteries.
- Ocular manifestations of PAN are uncommon but can be severe.
- Anterior ischemic optic neuropathy (AION) is a recognized, albeit rare, complication of systemic inflammatory diseases.
Observation:
- A patient with diagnosed polyarteritis nodosa was undergoing treatment with cytostatics and corticosteroids.
- The patient presented with symptoms indicative of an ocular vascular event.
Findings:
- The patient developed anterior ischemic optic neuropathy (AION).
- This represents a rare, previously undocumented manifestation of polyarteritis nodosa.
- The occurrence suggests a potential link between PAN, its treatment, and AION.
Implications:
- This case expands the known spectrum of polyarteritis nodosa complications.
- It underscores the importance of vigilant ophthalmological monitoring in patients with PAN, even during treatment.
- Further research may elucidate the specific mechanisms linking PAN, immunosuppressive therapy, and ischemic optic neuropathy.
