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Updated: Jun 5, 2025
Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
Sex differences in a Brazilian sample of patients with inflammatory bowel disease
Khadija Assis Pascholatto1, Laura Ribeiro Santos1, Thelma Larocca Skare1
1Mackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.
Background:
Inflammatory bowel diseases such as Crohn's disease and ulcerative colitis are influenced by environmental and immunological factors and may differ according to the patient's sex.
Objective:
The objective was to study the differences in the clinical profile of a Brazilian sample of inflammatory bowel disease patients according to sex.
Methods:
Retrospective study with chart review of 158 inflammatory bowel disease patients (43 with Crohn's disease and 115 with ulcerative colitis) from a single university hospital in southern Brazil.
Results:
The Crohn's disease sample showed a female/male ratio of 2.1, and the sample of ulcerative colitis showed a ratio of 1.5. The only significant difference found in the clinical profile was an increased constipation rate in female patients with ulcerative colitis. No other differences in epidemiological, symptom profile, or treatment could be detected.
Conclusions:
More females with inflammatory bowel diseases sought healthcare facilities compared to males. The only notable difference was a higher incidence of constipation symptoms among females; all other aspects were similar between the sexes.
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