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Navigating the terrain between research and practice: a Collaborative Research Network (CRN) case study in diabetes
Margaret A Handley1, Hali Hammer, Dean Schillinger
1Department of Family and Community Medicine, San Francisco General Hospital, University of California-San Francisco, 995 Portrero Avenue, San Francisco, CA 94110, USA. handleym@fcm.ucsf.edu
Journal of the American Board of Family Medicine : JABFM
|February 24, 2006
Summary
Translational research in diabetes self-management support requires careful planning. This case study highlights key decisions and trade-offs in designing and implementing practical clinical trials for diabetes.
Area of Science:
- Translational Science
- Clinical Research
- Diabetes Self-Management
Background:
- Real-world clinical trials enhance research-to-practice translation.
- Limited case studies detail design and implementation decisions in practical clinical trials.
Purpose of the Study:
- To outline the IDEALL (Improving Diabetes Efforts Across Language and Literacy) Project.
- To present a case study on translational diabetes research.
- To explore recruitment, intervention selection, and integration decisions in practice.
Main Methods:
- Case study of the IDEALL Project.
- Examined patient, clinician, and practice recruitment strategies.
- Assessed intervention selection and integration into primary care.
Main Results:
- Recruitment adapted to Institutional Review Board (IRB) restrictions.
- Population databases and diverse clinic types enhanced patient and clinic diversity.
- An adjunctive model facilitated intervention delivery but raised sustainability concerns.
Conclusions:
- Practical clinical trials involve complex strategic decisions and trade-offs.
- Describing design choices is crucial for interpreting translational research findings.