Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary arterial hypertension.

Lewis J Rubin1

  • 1University of California, San Diego, School of Medicine, 9300 Campus Point Drive, La Jolla, CA 92037, USA. ljrubin@ucsd.edu

Proceedings of the American Thoracic Society
|February 24, 2006
PubMed
Summary

Pulmonary arterial hypertension (PAH) involves injury to lung blood vessels, raising pressure. Recent progress enhances understanding of PAH causes and treatments, improving patient outlook.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Gut Feeling: Does the Gastrointestinal Tract Microbiome Contribute to the Pro-Inflammatory State in PAH?

JACC. Basic to translational science·2025
Same author

Hypoxemia with Sotatercept.

American journal of respiratory and critical care medicine·2025
Same author

Pulmonary Hypertension: A Personal Journey.

Pulmonary circulation·2025
Same author

The Seventh World Symposium on Pulmonary Hypertension: our journey to Barcelona.

The European respiratory journal·2024
Same author

Risk stratification and treatment goals in pulmonary arterial hypertension.

The European respiratory journal·2024
Same author

Is There a Role for Calcium Channel Blockers in the Contemporary Treatment Paradigm for Pulmonary Arterial Hypertension?

Circulation·2024

Area of Science:

  • Cardiology
  • Pulmonology
  • Vascular Medicine

Background:

  • Pulmonary arterial hypertension (PAH) is characterized by elevated pulmonary arterial pressure due to pulmonary vasculature injury.
  • Significant advancements in understanding PAH pathogenesis and treatment have occurred in the last decade.

Purpose of the Study:

  • To review the classification of diseases associated with PAH.
  • To summarize the current understanding of PAH pathogenesis.
  • To outline contemporary therapeutic approaches for PAH.

Main Methods:

  • Literature review of recent studies on PAH classification.
  • Synthesis of current knowledge on PAH pathogenesis.
  • Analysis of contemporary treatment strategies for PAH.

Main Results:

  • The classification of PAH encompasses diverse underlying conditions.
  • Pathogenesis involves complex molecular and cellular mechanisms.
  • Current therapy involves a multi-faceted approach targeting various pathways.

Conclusions:

  • PAH classification aids in understanding disease heterogeneity.
  • Advances in pathogenesis research inform therapeutic development.
  • Contemporary treatment strategies aim to improve outcomes in PAH.

Related Experiment Videos