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Published on: December 15, 2011
Henoch-Schönlein purpura in north-eastern Turkey
Murat Cakir1, Fazil Orhan, Ilke Mungan
1Department of Pediatrics, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey. muratcak@hotmail.com
Annals of Tropical Paediatrics
|February 24, 2006
Summary
Henoch-Schönlein purpura (HSP) in children is typically benign. This study found that while HSP can affect older children, renal manifestations were less common, and hypertension occurred without urinary findings.
Area of Science:
- Pediatrics
- Nephrology
- Rheumatology
Background:
- Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in childhood.
- Epidemiological and clinical data on HSP can vary geographically and over time.
Purpose of the Study:
- To analyze the epidemiological and clinical characteristics of pediatric Henoch-Schönlein purpura (HSP) cases over a 10-year period.
- To compare these findings with international data on HSP in children.
Main Methods:
- Retrospective analysis of medical records for children aged 17 years or less diagnosed with HSP.
- Evaluation of epidemiological data (age, sex, season) and clinical features (skin, gastrointestinal, joint, renal manifestations).
Main Results:
- 116 children (63% boys) with a mean age of 8.9 years were included; one-third were over 10 years old.
- Gastrointestinal (55.1%) and joint (62.9%) manifestations were common. Renal involvement occurred in 31% of patients, with one progressing to end-stage renal disease.
- Recurrences were noted in 6.9% of patients. Preceding upper respiratory tract infections were reported in 13.7%.
Conclusions:
- Henoch-Schönlein purpura (HSP) is generally a self-limiting condition in children.
- Hypertension can occur in HSP patients even without urinary abnormalities.
- This study suggests HSP may affect older children in this region with a lower incidence of renal involvement compared to other populations.
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