Related Experiment Video
Updated: Aug 11, 2026
06:55
A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
Published on: November 7, 2018
Salmonella-associated deaths, Sweden, 1997-2003
Anders Ternhag1, Anna Törner, Karl Ekdahl
1Swedish Institute for Infectious Disease Control, Solna, Sweden. anders.ternhag@karolinska.se
Emerging Infectious Diseases
|February 24, 2006
Summary
Salmonella infection in Sweden increases mortality risk, particularly for domestically acquired cases. Infections acquired abroad did not show a significant excess death risk in this study.
Area of Science:
- Infectious Diseases
- Epidemiology
- Public Health
Background:
- Salmonella infections are a significant global health concern.
- Understanding the long-term mortality risks associated with Salmonella is crucial for public health interventions.
Purpose of the Study:
- To investigate the association between the origin of Salmonella infection (domestic vs. abroad) and excess mortality.
- To determine if Salmonella infection acquired within Sweden carries a different mortality risk compared to infections acquired internationally.
Main Methods:
- Registry-based matched cohort study design.
- Inclusion of 25,060 individuals infected abroad and 5,139 infected within Sweden.
- Analysis of standardized mortality ratios to assess excess deaths.
Main Results:
- Individuals infected with Salmonella within Sweden exhibited an increased standardized mortality ratio.
- No excess risk of death was observed in individuals who acquired Salmonella infection abroad.
- The origin of infection significantly impacts post-Salmonella mortality outcomes.
Conclusions:
- Domestic Salmonella infections in Sweden are associated with a higher risk of mortality.
- International travel-associated Salmonella infections do not appear to confer an increased mortality risk.
- Public health strategies may need to differentiate based on the source of Salmonella infection.
Related Concept Videos
01:23Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
01:29Sources of Food Contamination
Contamination of food by microbial agents and natural toxins poses significant risks to public health. These hazards can be introduced at various points across the food supply chain, ranging from environmental sources to processing and storage stages. Understanding these contamination pathways is critical for developing strategies to ensure food safety.Seafood is particularly vulnerable to contamination through both environmental exposure and microbial colonization. Toxins from harmful algal...
01:18Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
01:25Cholera
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...