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[Myxofibrosarcoma associated with anetoderma].

G Chaby1, V Viseux, D Chatelain

  • 1Service de Dermatologie et Vénéréologie, Hôpital Sud, Amiens. chaby.guillaume@chu-amiens.fr

Annales De Dermatologie Et De Venereologie
|February 24, 2006
PubMed
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A rare case of secondary anetoderma, a skin condition, was found to be associated with myxofibrosarcoma, a type of malignant tumor. This highlights the importance of thorough biopsy for unusual skin lesions.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Secondary anetoderma is infrequently linked to malignant cutaneous tumors.
  • The association between secondary anetoderma and myxofibrosarcoma has not been previously documented.

Observation:

  • An 80-year-old woman presented with a flesh-colored lesion on her buttock, initially appearing soft and protuberant.
  • Pathological examination revealed myxofibrosarcoma with focal loss of elastic fibers in the overlying dermis.
  • A recurrence at the same site was observed one year later.

Findings:

  • The case demonstrates a rare instance of secondary anetoderma preceding a diagnosis of myxofibrosarcoma.
  • Myxofibrosarcoma, previously known as myxoid malignant fibrous histiocytoma, is characterized by a significant myxoid stroma.

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  • This malignant tumor has a high recurrence rate (nearly two-thirds) and a notable metastasis rate (one-fourth).

    • Implications:

    • An acquired anetodermic lesion can be an indicator of an underlying malignant tumor.
    • Systematic deep and large biopsies are crucial when encountering this type of anetoderma.
    • Early detection and diagnosis are vital for managing myxofibrosarcoma.