Clostridium welchii corneal ulcer--a case report

Area of Science:

• Ophthalmology
• Microbiology
• Infectious Diseases

Background:

• Clostridial infections typically involve trauma and polymicrobial infections.
• Ocular involvement, particularly isolated corneal ulcers, is rare for Clostridium welchii.
• Achromobacter species can be opportunistic pathogens in ocular infections.

Purpose of the Study:

• To report a unique case of corneal ulcer caused by Clostridium welchii and Achromobacter in a pediatric patient.
• To emphasize the rarity of isolated corneal involvement in clostridial infections without trauma.
• To review the bacteriology and diagnostic considerations for Clostridium welchii in ocular infections.

Main Methods:

• Case presentation of a 10-year-old Nigerian boy with corneal ulcer.
• Isolation and identification of Clostridium welchii and Achromobacter from corneal scrapings.
• Review of literature on clostridial ocular infections, including necessary media and symbiotic relationships.

Main Results:

• Clostridium welchii and Achromobacter were successfully isolated from the corneal ulcer.
• The patient had no history of trauma, making the presentation atypical.
• The infection was confined to the cornea, with no other systemic involvement.

Conclusions:

• Clostridium welchii can cause isolated corneal ulcers, even without preceding trauma.
• Specific microbiological media and techniques are crucial for isolating Clostridium welchii.
• Understanding the symbiotic relationship with other bacteria, like Achromobacter, aids in managing such rare infections.
• The patient experienced an uneventful recovery, demonstrating successful treatment outcomes.