Acute pulmonary embolism: imaging in the emergency department

Acute pulmonary embolism (PE) is a life-threatening condition that requires accurate diagnostic imaging. Morbidity and mortality that result from PE can be reduced significantly if appropriate treatment is initiated early; this makes timely diagnosis imperative. Historically, the gold standard for the imaging of PE has been pulmonary angiography. Rapid advances in radiology and nuclear medicine have led to this modality largely being replaced by noninvasive techniques, most frequently multidetector helical CT pulmonary angiography (CTPA). In cases in which CTPA is contraindicated, other modalities for diagnosis of PE include nuclear ventilation perfusion scanning, magnetic resonance pulmonary angiography, duplex Doppler ultrasonography for deep venous thrombosis, and echocardiography. This article reviews the literature on the role of these imaging modalities in the diagnosis of PE.