The role of left ventricular long-axis contraction in patients with asymptomatic aortic regurgitation

Ioannis A Paraskevaidis1, Dimitrios Tsiapras, Stamatis Kyrzopoulos

  • 1Second Department of Cardiology, Onassis Cardiac Surgery Center, Attiko General Hospital, Medical University, Athens, Greece. iparas@otenet.gr

Insights

Assessing left ventricular long axis contraction in asymptomatic aortic regurgitation (AR) patients can reveal reduced function. Systolic wave velocity at the mitral annulus is a key indicator of this subnormal status.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Echocardiography

Background:

  • Chronic aortic regurgitation (AR) can affect left ventricular function.
  • Asymptomatic patients require methods to detect early functional decline.

Purpose of the Study:

  • To investigate the role of left ventricular long axis contraction in asymptomatic AR.
  • To identify predictors of subnormal left ventricular function in these patients.

Main Methods:

  • Tissue Doppler imaging was performed in 84 asymptomatic AR patients.
  • Left ventricular end-diastolic pressure (LVEDP) and end-diastolic wall stress (EDWS) were calculated during catheterization.

Main Results:

  • Systolic wave maximal velocity (Sv) at the lateral mitral annulus (9 cm/s) best predicted exercise ejection fraction changes.
  • Patients with Sv > 9 cm/s had lower LVEDP and EDWS compared to those with Sv < 9 cm/s (P < .01).

Conclusions:

  • Left ventricular long axis contraction assessment at rest can identify subnormal function in asymptomatic AR.
  • This evaluation may help in early detection and management of AR-related cardiac changes.
Abstract

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