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The role of left ventricular long-axis contraction in patients with asymptomatic aortic regurgitation
Ioannis A Paraskevaidis1, Dimitrios Tsiapras, Stamatis Kyrzopoulos
1Second Department of Cardiology, Onassis Cardiac Surgery Center, Attiko General Hospital, Medical University, Athens, Greece. iparas@otenet.gr
Insights
Assessing left ventricular long axis contraction in asymptomatic aortic regurgitation (AR) patients can reveal reduced function. Systolic wave velocity at the mitral annulus is a key indicator of this subnormal status.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Echocardiography
Background:
- Chronic aortic regurgitation (AR) can affect left ventricular function.
- Asymptomatic patients require methods to detect early functional decline.
Purpose of the Study:
- To investigate the role of left ventricular long axis contraction in asymptomatic AR.
- To identify predictors of subnormal left ventricular function in these patients.
Main Methods:
- Tissue Doppler imaging was performed in 84 asymptomatic AR patients.
- Left ventricular end-diastolic pressure (LVEDP) and end-diastolic wall stress (EDWS) were calculated during catheterization.
Main Results:
- Systolic wave maximal velocity (Sv) at the lateral mitral annulus (9 cm/s) best predicted exercise ejection fraction changes.
- Patients with Sv > 9 cm/s had lower LVEDP and EDWS compared to those with Sv < 9 cm/s (P < .01).
Conclusions:
- Left ventricular long axis contraction assessment at rest can identify subnormal function in asymptomatic AR.
- This evaluation may help in early detection and management of AR-related cardiac changes.
Background:
We aimed to investigate the role of long axis contraction in patients with asymptomatic chronic aorta regurgitation (AR).
Methods:
In 84 consecutive patients (48 men, mean age 55.5 +/- 13.5 years) tissue Doppler imaging was performed. During catheterization, left ventricular end-diastolic pressure (LVEDP) and end-diastolic wall stress (EDWS) were calculated.
Results:
The best predictor for group membership (exercise ejection fraction increase > or < of 5%) is the systolic wave maximal velocity (Sv) at the lateral mitral annulus (9 cm/s). Patients with Sv > 9 cm/s (45 patients) formed group I, while 39 patients with Sv < 9 cm/s formed group II. LVEDP and EDWS were higher in group II (15.5 +/- 1.9 mm Hg and 214.8 +/- 233.3 g/cm2) than in group I (10.3 +/- 1.7 mmHg and 111.8 +/- 40.8 g/cm2), P = .0001 and P = .01, respectively.
Conclusion:
In patients with asymptomatic AR, the estimation of left ventricular long axis contraction at rest, can unmask a subnormal left ventricular functional status.
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