Multiple fiber laser-induced thermotherapy for ablation of large intrahepatic tumors
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Updated: Aug 11, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Liesbeth M Veenendaal1, Arjan de Jager, Gerard Stapper
1Department of Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Objective:
The aim of this study was to test three techniques used simultaneously to increase lesion size.
Background Data:
Laser-induced thermotherapy (LITT) is a method of local tumor ablation, which may prolong survival in patients with unresectable liver metastases. The main limitation has been the production of lesions with sufficient tumor-free margin.
Methods:
LITT treatment was performed with water-cooled, multiple fiber application and hepatic blood flow occlusion in six patients with unresectable intrahepatic metastases. Response was measured by computed tomography scan.
Results:
In all patients, tumors were effectively ablated. In two patients with colorectal metastases, lesions up to 8.6 cm could be created.
Conclusion:
The use of watercooled multiple fiber application and hepatic inflow occlusion makes LITT an effective ablative method, expanding the treatment options for patients with large intrahepatic masses.
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