Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Endogenous Cushing's syndrome].

Johan Arild Evang1, Sven M Carlsen, Johan Svartberg

  • 1Endokrinologisk seksjon, Medisinsk avdeling, Rikshospitalet, 0027 Oslo. johan.arild.evang@rikshospitalet.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|March 1, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical management of vestibular schwannoma - what's the evidence?

Acta neurochirurgica·2026
Same author

Targeted proteomics reveals novel biomarkers of disease activity and inflammation in acromegaly.

European journal of endocrinology·2026
Same author

Individualized management of primary hyperparathyroidism.

Journal of internal medicine·2026
Same author

Prevalence, risk factors and management of bone complications in Cushing's syndrome across Europe. Data from the European Registry on Cushing's syndrome (ERCUSYN).

Annales d'endocrinologie·2026
Same author

Steroid-dependent metabolic rewiring reveals novel therapeutic and imaging approaches for glioblastoma.

Science advances·2026
Same author

Use of total calcium in hypoparathyroidism: a pragmatic approach but with limitations.

European journal of endocrinology·2025

Endogenous Cushing's syndrome, caused by excess cortisol, presents with varied symptoms. Early diagnosis and surgical intervention are crucial for managing this serious condition.

Area of Science:

  • Endocrinology
  • Internal Medicine

Context:

  • Untreated endogenous Cushing's syndrome (ECS) is associated with significant morbidity and mortality.
  • Advances in diagnostic procedures enhance the accuracy of ECS assessment.
  • This review outlines diagnostic strategies and treatment options for suspected ECS.

Purpose:

  • To detail the recommended diagnostic tests for suspected endogenous Cushing's syndrome.
  • To provide an overview of current treatment modalities for ECS.

Summary:

  • ECS results from elevated cortisol due to ACTH overproduction or adrenocortical pathology.
  • Key symptoms include central obesity, muscle weakness, striae, menstrual irregularities, osteoporosis, and impotence.
  • Diagnostic challenges necessitate a combination of dynamic tests, with urinary free cortisol and overnight dexamethasone suppression tests as initial steps.

Related Experiment Videos

  • Midnight salivary cortisol shows promise as an alternative diagnostic marker.
  • Surgical resection is the primary treatment for endogenous Cushing's syndrome.

    • Impact:

    • Improved diagnostic accuracy for Cushing's syndrome.
    • Timely identification and management of a high-morbidity condition.
    • Guidance for clinicians on evaluating and treating patients with suspected ECS.