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Updated: Aug 11, 2026

Electrophoretic Analysis of Replication Through Structure-Prone DNA Repeats Within the SV40-Based Human Episome
Published on: September 13, 2024
Identifying repeat domains in large genomes
Degui Zhi1, Benjamin J Raphael, Alkes L Price
1Bioinformatics Program, University of California, San Diego, CA 92093-0419, USA. dzhi@ucsd.edu
Abstract:
We present a graph-based method for the analysis of repeat families in a repeat library. We build a repeat domain graph that decomposes a repeat library into repeat domains, short subsequences shared by multiple repeat families, and reveals the mosaic structure of repeat families. Our method recovers documented mosaic repeat structures and suggests additional putative ones. Our method is useful for elucidating the evolutionary history of repeats and annotating de novo generated repeat libraries.
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