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Perioperative anxiety and postoperative behavioural disturbances in children: comparison between induction techniques

N Bal1, F Saricaoglu, S Uzun

  • 1Department of Anaesthesiology and Reanimation, Hacettepe University Faculty of Medicine, Ankara, Turkey.

European Journal of Anaesthesiology
|March 2, 2006
PubMed

Insights

Adding a sub-hypnotic dose of propofol to sevoflurane induction did not reduce postoperative behavioral issues in children. Preoperative anxiety was linked to increased behavioral disturbances after surgery.

Area of Science:

  • Pediatric Anesthesiology
  • Pharmacology
  • Behavioral Science

Background:

  • Postoperative behavioral disturbances are common in children.
  • Sevoflurane and propofol are widely used anesthetic agents for pediatric procedures.

Purpose of the Study:

  • To evaluate if sub-hypnotic propofol reduces postoperative behavioral disturbances in children undergoing sevoflurane induction.
  • Comparison between sevoflurane induction, intravenous propofol induction, and sevoflurane with sub-hypnotic propofol.

Main Methods:

  • 120 children (2-10 years) were randomly assigned to three groups: sevoflurane inhalation, intravenous propofol, or sevoflurane with sub-hypnotic propofol.
  • Anxiety was assessed at induction and post-emergence.
  • Postoperative behavioral disturbances were evaluated using questionnaires completed by parents.

Main Results:

  • Anxiety levels were high at induction across all groups.
  • No significant difference in anxiety was observed at other time points.
  • A correlation was found between preoperative anxiety and postoperative behavioral disturbances.
  • Fewer behavioral disturbances like nightmares were noted in the intravenous propofol group.

Conclusions:

  • Sub-hypnotic propofol added to sevoflurane induction did not decrease postoperative behavioral disturbances.
  • Intravenous propofol induction may be associated with fewer behavioral issues compared to sevoflurane-based anesthesia.
Abstract

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