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Blood pressure control in patients with chronic renal insufficiency in Spain: a cross-sectional study

Rafael Marín1, Francisco Fernández-Vega, Manuel Gorostidi

  • 1Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain. rmarín@hca.es

Journal of Hypertension
|March 2, 2006
PubMed

Insights

Blood pressure control is inadequate in patients with chronic renal insufficiency (CRI), despite frequent combination therapy. Increased antihypertensive drug use, statins, and antiplatelet therapy are needed for better renal and cardiovascular outcomes.

Area of Science:

  • Nephrology
  • Cardiology
  • Hypertension Management

Background:

  • Hypertension control remains a challenge in patients with chronic renal insufficiency (CRI).
  • Existing therapeutic advances have not fully addressed the strict control of blood pressure in this population.
  • Cardiovascular comorbidities are highly prevalent in patients with CRI.

Purpose of the Study:

  • To assess blood pressure control rates in patients with chronic renal insufficiency (CRI).
  • To evaluate the control rates of proteinuria in CRI patients.
  • To determine the prevalence of cardiovascular comorbidities in this cohort.

Main Methods:

  • A multicenter, cross-sectional survey was conducted.
  • Unselected patients with CRI were recruited from outpatient nephrology clinics in Spain.
  • Data were collected between April and September 2003.

Main Results:

  • Only 17.4% of 2501 patients achieved blood pressure below 130/80 mmHg.
  • Poor blood pressure control was linked to older age, higher proteinuria, and elevated LDL cholesterol.
  • 48.3% had proteinuria <0.5 g/day; 75.9% received renin-angiotensin system inhibitors; 41.9% used ≥3 antihypertensives.

Conclusions:

  • Blood pressure control in CRI patients is inadequate, even with frequent combination therapy.
  • Therapies commonly included ACE inhibitors or ARBs.
  • Increased antihypertensive drug dosage, statins, and antiplatelet therapy are recommended to improve outcomes.
Abstract

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