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Updated: Jul 30, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
Published on: November 2, 2018
Crystallization and X-ray crystallographic analysis of human STAT1
1Department of Biochemistry and Molecular Biology, The University of Texas M. D. Anderson Cancer Center, Box 117, Houston, TX 77030, USA.
Abstract:
Unphosphorylated human STAT1 (1-683) has been crystallized in the presence of a phosphopeptide derived from the alpha-chain of human interferon gamma (IFNgamma) receptor. A complete data set has been collected from a KAu(CN)2-derivatized and dehydrated crystal. The crystal belonged to space group P6(1)22, with unit-cell parameters a = b = 102.6, c = 646.5 A, alpha = beta = 90, gamma = 120 degrees.
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