Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Community-associated methicillin-resistant Staphylococcus aureus causing chronic pneumonia.

Iram Enayet1, Ali Nazeri, Leonard B Johnson

  • 1St. John Hospital and Medical Center, Detroit, Michigan, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|March 3, 2006
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Candidozyma auris</i> susceptibility from Michigan hospitals to manogepix, rezafungin and nine other antifungal agents.

JAC-antimicrobial resistance·2026
Same author

Advantage of Amnion Dressing (Biological Dressing) + Silver Sulfadiazine Cream <i>vs.</i> Standard Silver Sulfadiazine Cream Dressings in Acute Deep Second-Degree and Third-Degree Burn Wounds: a Single Center Experience.

Maedica·2025
Same author

What Is Bird Flu?

JAMA·2025
Same author

Clinical and Drug Resistance Characteristics of <i>Providencia</i> Infections.

Microorganisms·2024
Same author

Recurrent streptococcal toxic shock syndrome due to distinct episodes of <i>Streptococcus dysgalactiae</i> and <i>Streptococcus agalactiae</i> septic arthritis.

BMJ case reports·2024
Same author

Rhodomyrtone: a new anti-<i>Staphylococcus aureus</i> agent against resistant strains.

JAC-antimicrobial resistance·2024

A prolonged pneumonia case in a young woman was linked to a specific Methicillin-resistant Staphylococcus aureus (MRSA) strain. This USA 300 MRSA isolate carried genes for Panton-Valentine leukocidin, contributing to the severe lung infection.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Microbiology

Background:

  • Pneumonia is a significant respiratory infection with diverse etiologies.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a notable cause of community- and hospital-acquired infections.
  • Nodular pulmonary infiltrates can indicate various underlying lung pathologies.

Observation:

  • A young woman presented with a 3-month history of pneumonia.
  • The patient exhibited predominantly nodular pulmonary infiltrates on imaging.
  • Sputum cultures consistently identified Methicillin-resistant Staphylococcus aureus.

Findings:

  • Pulsed-field gel electrophoresis confirmed the MRSA isolate as the USA 300 strain.
  • The identified MRSA strain harbored the staphylococcal cassette chromosome mec type IV (SCCmec IV) gene.

Related Experiment Videos

  • The isolate also carried genes encoding Panton-Valentine leukocidin (PVL).

    • Implications:

    • This case highlights the potential for USA 300 MRSA, particularly PVL-positive strains, to cause prolonged and severe pneumonia.
    • Understanding the genetic makeup of MRSA isolates is crucial for effective treatment and infection control.
    • Further research into the clinical manifestations and management of PVL-positive MRSA pneumonia is warranted.