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Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
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The experience of treating patients with thrombotic thrombocytopenic purpura with solvent detergent plasma

Leo J McCarthy

    British Journal of Haematology
    |March 4, 2006
    PubMed
    Abstract

    No abstract available in PubMed .

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    Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...

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